Peptiter / DiscoveryLab
Proof
Mechanism proof

Evidence tutor — retrieval-grounded peptide reasoning.

A retrieval-grounded tutor for peptide reasoning, with citations bound to the underlying evidence.

Evidence-aware tutor

A peptide tutor grounded by retrieval contracts and citations.

DiscoveryLab includes a local peptide tutor backed by retrieval, citations, and quality gates, plus a Bedrock Claude / Kendra grounding contract for hosted evidence retrieval. It supports research reasoning around design choices, receptor rationale, peptide families, pathway mechanisms, Lean audit receipts, perturbation evidence, uncertainty, contraindication concerns, and evidence gaps.

The tutor supports research reasoning; it does not replace expert review, prescriber judgment, or wet-lab validation.
tutor · session DL-2841retrieval · 14 sources · local fallback + Bedrock/Kendra plan
researcher
Why prefer a dual GLP-1R / GIPR scaffold over GLP-1R alone for this program?
tutor · evidence-gated

Dual agonism at GLP-1R and GIPR has shown additive effects on glycemic control and weight loss in published preclinical and Phase 2/3 programs [1][2]. For this condition mapping, family DL-FAM-019 retains GLP-1R primary contact residues while introducing a GIPR-permissive C-terminal motif [3]. Uncertainty: long-term receptor desensitization data is incomplete [4].

[1]Frias et al., 2021 · NEJM
[2]Rosenstock et al., 2023
[3]Internal: family DL-FAM-019 spec
[4]Open question · evidence gap